The only permanent is impermanence
The only sure thing is death.
These are the only two things we really know for sure!
We can take these facts and live scared. Scared of loss, scared of change, scared of the end or we can allow these facts to free us. Free us to enjoy every moment we have, free us to embrace the changes and challenges we face, Free us to live fully in the moment, which ever moment it may be. Because no matter how good or bad it can change instantly and no matter how good or bad it can end instantly.
The choice on how you view it and how you live is up to you!